Frightful must it be, for supremely frightful would be the effect of any human endeavor to mock the stupendous mechanism of the Creator of the world.

What does Mary Shelley mean by this statement from her introduction to Frankenstein?

God punishes anyone who attempts to disobey.

Creation is the sole realm of God.

It is natural for humans to want to play God.

Scientists can make better human beings.

The answer is " Creation is the sole realm of God"