The switch of one B cell from producing one class of antibody to another class of antibody that is responsive to the same antigen is due to _______. A. the rearrangement of V region genes in that clone of responsive B cells B. a switch in the kind of antigen-presenting cell that is involved in the immune response C. a patient's reaction to the first kind of antibody made by the plasma cells D. the rearrangement of immunoglobulin heavy-chainC region DNA

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23-08-2022
Biology

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The switch of one B cell from producing one class of antibody to another class of antibody that is responsive to the same antigen is due to _______. A. the rearrangement of V region genes in that clone of responsive B cells B. a switch in the kind of antigen-presenting cell that is involved in the immune response C. a patient's reaction to the first kind of antibody made by the plasma cells D. the rearrangement of immunoglobulin heavy-chainC region DNA

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tushargupta0691 tushargupta0691 · Answer 1 · 2022-08-27T05:07:01+02:00

The switch of one B cell from producing one class of antibody to another class of antibody that is responsive to the same antigen is due to the rearrangement of immunoglobulin heavy-chains region DNA

Types of Immunoglobulin

Immunoglobulins were discovered in 1890 by two immunologists, Emil von Behring and Kitasato Shibasaburo, and were first referred to as neutralizing substances.

Immunoglobulins are glycoproteins that play a crucial part in the immune system's maintenance.
Immunoglobulins, often known as antibodies, are highly specific proteins that are released in large quantities by plasma cells in response to harmful antigens.

Immunoglobulins are Y-shaped globular proteins with a molecular weight of 150kDa and a size of roughly 10nm.

All immunoglobulins share four polypeptide subunits
Two hefty chains and two light chains that are similar.
A disulfide bridge connects the polypeptide chains, forming a Y-shaped structure.

This Y-shaped structure is split into two parts:

The bottom section is referred to as a constant zone & top, the two-arm portion is referred to as a variable region.

Hence, the correct answer is option D

Learn more about immunoglobulins here,

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